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Posted on by Dr. Alex Tan

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Written by Dr. Alex Tan

Dr. Alex Tan is the clinical director of Compass Eye Care. He graduated from the University of California Riverside with a bachelor’s degree in psycho biology. He then pursued his doctorate at the Illinois College of Optometry where he graduated and earned honors in all of his clinical rotations. After graduation, he received extra training by completing a 1-year residency in primary care optometry with an emphasis in family practice from the same institution.

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  37. priligy review youtube or a pharmaceutically acceptable salt thereof, wherein Q is CH or N; X is N or C R X; one of Y 1, Y 2, Z 1, and Z 2 is N, and the other three are C; R 1 is D, R, R D, NR 2, NRR D, N R D 2, N R C O NR 2, N R C NR NR 2, N R C O NRR D, N R C NR NRR D, OR, or OR D; R 2 is H, R C, N R C O Cy 2, N R S O 2 Cy 2, N R Cy 2, OCy 2, SCy 2, or Cy 2; R 3 is H, halogen, or C 1 6 aliphatic; or R 2 and R 3 are taken together with their intervening atoms to form a 4 7 membered partially unsaturated or aromatic ring having 0 3 heteroatoms independently selected from nitrogen, oxygen, and sulfur; wherein said ring is substituted with m instances of R 4; each of Cy 1 and Cy 2 is independently phenyl; a 5 6 membered monocyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; an 8 10 membered bicyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; a 3 7 membered saturated or partially unsaturated heterocyclic ring having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur; or a 3 7 membered saturated or partially unsaturated monocyclic carbocyclic ring; or a 7 12 membered saturated or partially unsaturated bicyclic heterocyclic ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur, wherein Cy 1 is substituted with n instances of R 5; and; wherein Cy 2 is substituted with p instances of R 6; L 1 is a covalent bond or a C 1 4 bivalent saturated or unsaturated, straight or branched hydrocarbon chain wherein one or two methylene units of the chain are optionally and independently replaced by C R 7 2, N R, N R C O, C O N R, N R S O 2, S O 2 N R, O, C O, OC O, C O O, S, S O or S O 2; each instance of R 4, R 5, R 6, and R 7 is independently R A or R B, and is substituted by q instances of R C; each instance of R A is independently oxo, halogen, CN, NO 2, OR, OR D, SR, NR 2, S O 2 R, S O 2 NR 2, S O R, S O NR 2, C O R, C O OR, C O NR 2, C O N R OR, OC O R, OC O NR 2, N R C O OR, N R C O R, N R C O NR 2, N R C NR NR 2, N R S O 2 NR 2, or N R S O 2 R; each instance of R B is independently C 1 6 aliphatic; phenyl; a 5 6 membered monocyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; an 8 10 membered bicyclic heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; a 3 7 membered saturated or partially unsaturated carbocyclic ring; a 3 7 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur; or a 7 12 membered saturated or partially unsaturated bicyclic heterocyclic ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; each instance of R C is independently oxo, halogen, CN, NO 2, OR, SR, NR 2, S O 2 R, S O 2 NR 2, S O R, S O NR 2, C O R, C O OR, C O NR 2, C O N R OR, OC O R, OC O NR 2, N R C O OR, N R C O R, N R C O NR 2, N R C NR NR 2, N R S O 2 NR 2, or N R S O 2 R or an optionally substituted group selected from C 1 6 aliphatic, phenyl, a 3 7 membered saturated or partially unsaturated heterocyclic ring having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur, and a 5 6 membered heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; R D is a C 1 4 aliphatic group wherein one or more hydrogens are replaced by deuterium; R X is H, halogen, or C 1 6 aliphatic each R is independently hydrogen, or an optionally substituted group selected from C 1 6 aliphatic, phenyl, a 3 7 membered saturated or partially unsaturated heterocyclic having 1 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur, and a 5 6 membered heteroaryl ring having 1 4 heteroatoms independently selected from nitrogen, oxygen, and sulfur, or two R groups on the same nitrogen are taken together with their intervening atoms to form a 4 7 membered saturated, partially unsaturated, or heteroaryl ring having 0 3 heteroatoms, in addition to the nitrogen, independently selected from nitrogen, oxygen, and sulfur; and each of m, n, p, and q is independently 0, 1, 2, 3, or 4

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